Pathways to Biomedical Discovery
نویسندگان
چکیده
منابع مشابه
Pathways to Biomedical Discovery*
A biochemical pathway is a sequence of chemical reactions in a biological organism. Such pathways specify mechanisms that explain how cells carry out their major functions by means of molecules and reactions that produce regular changes. Many diseases can be explained by defects in pathways, and new treatments often involve finding drugs that correct those defects. This paper presents explanati...
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Among the pathways used by gram-negative bacteria for protein secretion, the autotransporter pathway represents a solution of impressive simplicity. Proteins are transported, independent of their nature as recombinant or native passengers, as long as the coding nucleotide sequence is inserted in frame between those of an N-terminal signal peptide and a C-terminal domain, referred to as the beta...
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ژورنال
عنوان ژورنال: Philosophy of Science
سال: 2003
ISSN: 0031-8248,1539-767X
DOI: 10.1086/375465